Effects of Qishe Pill, a compound traditional Chinese herbal medicine, on cervical radiculopathy: study protocol for a randomized controlled trial

摘要: Neck pain is a common symptom in most patients suffering from cervical radiculopathy. However, some conservative treatments are limited by their modest effectiveness. On the other hand, surgical intervention for disc disorders indicated when symptoms refractory to and neurological progressive. Many use complementary alternative medicine, including traditional Chinese address symptoms. The purpose of present study examine efficacy safety Qishe Pill, compound herbal neck with A multicenter, double-blind, randomized, placebo-controlled trial evaluate Pill proposed. will include 240 five sites across China diagnosed radiculopathy, according following inclusion criteria: age 18 65 or stiffness at least 2 weeks (neck disability index score 25 more) accompanying arm that radiates distally elbow. Qualified participants be randomly allocated into two groups: group placebo group. prescription medications (Qishe Pill/placebo) 3.75 g each twice day 28 consecutive days. primary outcome severity. Secondary outcomes functional status, patient satisfaction, adverse events as reported trial. composed processed Radix Astragali, Muscone, Szechuan Lovage Rhizome, Stephaniae Tetrandrae, Ovientvine, Calculus Bovis Artifactus. According modern research preparation standards, developed improve on various especially pain. As it has potential benefit treating pain, we designed prospective, randomized-controlled would like publish results conclusions later. If can alleviate without effects, may unique strategy treatment This registered ClinicalTrials.gov, NCT01274936