Promises, facts and challenges for graphene in biomedical applications
作者： Giacomo Reina , José Miguel González-Domínguez , Alejandro Criado , Ester Vázquez , Alberto Bianco
DOI: 10.1039/C7CS00363C
关键词:
摘要: The graphene family has captured the interest and imagination of an increasing number scientists working in different fields, ranging from composites to flexible electronics. In area biomedical applications, is especially involved drug delivery, biosensing tissue engineering, with strong contributions whole nanomedicine area. Besides interesting results obtained so far evident success, there are still many problems solve, on way manufacturing devices, including lack standardization production members. Control lateral size, aggregation state (single vs. few layers) oxidation (unmodified oxidized graphenes) essential for translation this material into clinical assays. Tutorial Review we critically describe latest developments materials field. We analyze graphene-based devices starting synthetic strategies, functionalization processibility protocols up final vitro vivo applications. also address toxicological impact limitations translating advanced tools. Finally, new trends guidelines future presented.
rsc.org
units.it参考文章(54)
Andy Nieto, Rupak Dua, Cheng Zhang, Benjamin Boesl, Sharan Ramaswamy, Arvind Agarwal, Three Dimensional Graphene Foam/Polymer Hybrid as a High Strength Biocompatible Scaffold Advanced Functional Materials. ,vol. 25, pp. 3916- 3924 ,(2015) , 10.1002/ADFM.201500876
Alberto Bianco, Hui-Ming Cheng, Toshiaki Enoki, Yury Gogotsi, Robert H. Hurt, Nikhil Koratkar, Takashi Kyotani, Marc Monthioux, Chong Rae Park, Juan M.D. Tascon, Jin Zhang, All in the graphene family – A recommended nomenclature for two-dimensional carbon materials Carbon. ,vol. 65, pp. 1- 6 ,(2013) , 10.1016/J.CARBON.2013.08.038
Sitansu Sekhar Nanda, Georgia C. Papaefthymiou, Dong Kee Yi, Functionalization of Graphene Oxide and its Biomedical Applications Critical Reviews in Solid State and Materials Sciences. ,vol. 40, pp. 291- 315 ,(2015) , 10.1080/10408436.2014.1002604
A. Servant, A. Bianco, M. Prato, K. Kostarelos, Graphene for multi-functional synthetic biology: the last 'zeitgeist' in nanomedicine. Bioorganic & Medicinal Chemistry Letters. ,vol. 24, pp. 1638- 1649 ,(2014) , 10.1016/J.BMCL.2014.01.051
Alberto Bianco, Graphene: safe or toxic? The two faces of the medal. Angewandte Chemie. ,vol. 52, pp. 4986- 4997 ,(2013) , 10.1002/ANIE.201209099
Zhen Li, Mengyuan He, Dangdang Xu, Zhihong Liu, Graphene materials-based energy acceptor systems and sensors Journal of Photochemistry and Photobiology C-photochemistry Reviews. ,vol. 18, pp. 1- 17 ,(2014) , 10.1016/J.JPHOTOCHEMREV.2013.10.002
Yongbin Zhang, Syed F. Ali, Enkeleda Dervishi, Yang Xu, Zhongrui Li, Daniel Casciano, Alexandru S. Biris, Cytotoxicity Effects of Graphene and Single-Wall Carbon Nanotubes in Neural Phaeochromocytoma-Derived PC12 Cells ACS Nano. ,vol. 4, pp. 3181- 3186 ,(2010) , 10.1021/NN1007176
M. C. Serrano, J. Patiño, C. García-Rama, M. L. Ferrer, J. L. G. Fierro, A. Tamayo, J. E. Collazos-Castro, F. del Monte, M. C. Gutiérrez, 3D free-standing porous scaffolds made of graphene oxide as substrates for neural cell growth Journal of Materials Chemistry B. ,vol. 2, pp. 5698- 5706 ,(2014) , 10.1039/C4TB00652F
Sowmya Viswanathan, Tharangattu N. Narayanan, Kiana Aran, Kathryn D. Fink, Jacobo Paredes, Pulickel M. Ajayan, Slawomir Filipek, Przemyslaw Miszta, H. Cumhur Tekin, Fatih Inci, Utkan Demirci, Pingzuo Li, Kirill I. Bolotin, Dorian Liepmann, V. Renugopalakrishanan, Graphene–protein field effect biosensors: glucose sensing Materials Today. ,vol. 18, pp. 513- 522 ,(2015) , 10.1016/J.MATTOD.2015.04.003
Min Yi, Zhigang Shen, A review on mechanical exfoliation for the scalable production of graphene Journal of Materials Chemistry. ,vol. 3, pp. 11700- 11715 ,(2015) , 10.1039/C5TA00252D