Mutagenic Effects of Iron Oxide Nanoparticles on Biological Cells

摘要: In recent years, there has been an increased interest in the design and use of iron oxide materials with nanoscale dimensions for magnetic, catalytic, biomedical, electronic applications. The manufacture nanoparticles (IONPs) consumer products as well industrial processes is expected to lead unintentional release IONPs into environment. impact on environment biological species not understood but remains a concern due chemical reactivity relative their bulk counterparts. This review article describes cellular genetic components. mutagenic may damage organism's ability develop or reproduce. To date, experimental evidence having interactions human cell lines including lymphoblastoids, fibroblasts, microvascular endothelial cells, bone marrow lung epithelial alveolar type II like bronchial skin hepatocytes, cerebral fibrosarcoma breast carcinoma cervix cells. Other Chinese hamster ovary mouse fibroblast murine Mytilus galloprovincialis sperm mice macrophages, hepatic renal tissue vero cells have also shown effects upon exposure IONPs. We further show influence microorganisms presence absence dissolved organic carbon. results shed light OPEN ACCESS Int. J. Mol. Sci. 2015, 16 23483 transformations undergo nature potential