The importance of hemodynamic considerations in essential hypertension.

摘要: Hypertension is a major risk factor for cardiovascular morbidity and mortality. Antihypertensive therapy consistently reduces complications from stroke congestive heart failure, whereas benefits the treatment of ischemic disease events are variable. Several plausible explanations, including hemodynamic hypotheses, have been put forth to account failure more favorably influence mortality disease. The effect hypertension on coronary probably much complex than simple elevation arterial pressure. Some these complexities include potential separate risks high total peripheral resistance, cardiac output, increased myocardial power that reflects pressure times flow, several structural functional vascular changes. These factors may act in concert unfavorably alter balance between oxygen supply demand. will be highlighted an attempt offer alternative or adjunctive pathophysiologic examinations high-risk subgroups obesity antihypertensive normalize rate events.