Assignment of the human gene encoding eukaryotic initiation factor 4E (EIF4E) to the region q21-25 on chromosome 4.

作者: Robin M. Jones , Marcy E. MacDonald , John Branda , Michael R. Altherr , David N. Louis

DOI: 10.1007/BF02721373

关键词:

摘要: We recently cloned genomic sequences containing the promoter region for messenger RNA cap binding protein (eIF4E). As rate-limiting step in translation, eukaryotic initiation factor 4E is important cellular growth control. Using oligonucleotide primers specific polymerase chain reactions (PCR), we amplified human gene a chromosome 4-specific human/rodent somatic cell panel. This panel mapped single copy eIF4E 4q21 to 4q25.

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