The near absence of osteoporosis treatment in older men with fractures.

作者: Adrianne C. Feldstein , Gregory Nichols , Eric Orwoll , Patricia J. Elmer , David H. Smith

DOI: 10.1007/S00198-005-1950-0

关键词:

摘要: The burden of osteoporotic fractures in older men is significant. objectives our study were to: (1) characterize with associated osteoporosis, (2) determine if medication treatment rates for osteoporosis are improving and (3) identify patient, healthcare benefit utilization, clinician characteristics that significantly treatment. This retrospective cohort assessed 1,171 aged 65 or any new fracture between 1 January 1998 30 June 2001 a non-profit health maintenance organization the United States. Multiple logistic regression was used to evaluate pre-fracture factors their association 6-month post-fracture period. main outcome measure pharmacologic 6 months after index fracture. Subjects’ average age 76.7 years; 3.3% had diagnosis 15.2% secondary osteoporosis. Only 7.1% population 16.0% those hip vertebral received following fracture, did not improve over time. In multivariate model, drug higher value on Charlson Comorbidity Index (odds ratio 1.26, 95% confidence interval 1.05–1.51), having an 8.11, 3.08–21.3), chronic glucocorticoid use 5.37, 2.37–12.2) 16.6, 7.8–31.4). Bone mineral density measurement rare ( n =13, 1.1%). Our findings suggest there under-ascertainment under-treatment modifiable causes fractures. Information systems merging diagnostic information can help delineate gaps patient management. Interventions showing promise other conditions should be evaluated care

参考文章(54)
Eric S. Orwoll, Robert F. Klein, Therapy for Osteoporosis in Men Humana Press, Totowa, NJ. pp. 251- 269 ,(1996) , 10.1007/978-1-4612-0221-9_21
C H Hennessy, M M Desai, P Zhang, Surveillance for morbidity and mortality among older adults--United States, 1995-1996. MMWR. CDC surveillance summaries : Morbidity and mortality weekly report. CDC surveillance summaries / Centers for Disease Control. ,vol. 48, pp. 7- 25 ,(1999)
Clare D. Edman, Estrogen Replacement Therapy Obstetrics & Gynecology. ,vol. 58, pp. 267- 275 ,(1983) , 10.1007/978-1-4612-5525-3_6
Kristi J. Ferguson, Estrogen Replacement Therapy Archives of Internal Medicine. ,vol. 149, pp. 133- 136 ,(1989) , 10.1001/ARCHINTE.1989.00390010123016
Carolyn M. Klotzbuecher, Philip D. Ross, Pamela B. Landsman, Thomas A. Abbott, Marc Berger, Patients with Prior Fractures Have an Increased Risk of Future Fractures: A Summary of the Literature and Statistical Synthesis Journal of Bone and Mineral Research. ,vol. 15, pp. 721- 739 ,(2010) , 10.1359/JBMR.2000.15.4.721
P. D. Ross, Osteoporosis. Frequency, consequences, and risk factors Archives of Internal Medicine. ,vol. 156, pp. 1399- 1411 ,(1996) , 10.1001/ARCHINTE.156.13.1399
Hosam K Kamel, Mohammad S Hussain, Syed Tariq, Horace M Perry, John E Morley, Failure to diagnose and treat osteoporosis in elderly patients hospitalized with hip fracture The American Journal of Medicine. ,vol. 109, pp. 326- 328 ,(2000) , 10.1016/S0002-9343(00)00457-5
Murray J. Favus, David M. Slovik, Primer on the metabolic bone diseases and disorders of mineral metabolism Endocrinologist. ,vol. 4, pp. 148- 149 ,(1994) , 10.1097/00019616-199403000-00012
Nancy Fox Ray, Julien K. Chan, Mae Thamer, L. Joseph Melton, Medical Expenditures for the Treatment of Osteoporotic Fractures in the United States in 1995: Report from the National Osteoporosis Foundation Journal of Bone and Mineral Research. ,vol. 12, pp. 24- 35 ,(1997) , 10.1359/JBMR.1997.12.1.24