Lipoprotein Lipase Activity in the Pathological Metabolism of Lipoproteins

作者: Paul N. Durrington

DOI: 10.1007/978-1-4899-0993-0_16

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摘要: Many of the clinical features defective lipoprotein lipase activity were known well before present century, particularly milky appearance serum. This was as result use venesection a means treatment such disorders abdominal pain, diabetes, alcoholism, and glomerulonephritis (reference 1 cites many early reports). The syndrome familial deficiency (FLLD) not, however, first clearly described until 1930’s [2, 3]. Havel Gordon showed that its basis [4]. Only recently has it also been appreciated similar can from defect in apolipoprotein CII, circulating activator [5]. Lipoprotein with an autoimmune [6].

参考文章(29)
Havel Rj, Pathogenesis, differentiation and management of hypertriglyceridemia. Advances in internal medicine. ,vol. 15, pp. 117- ,(1969)
John D. Brunzell, Johan H. Auwerx, Samir S. Deeb, Hans Will, John E. Hokanson, Gisela Stahnke, Stephan P. Babirak, Coexistence of abnormalities of hepatic lipase and lipoprotein lipase in a large family. American Journal of Human Genetics. ,vol. 46, pp. 470- 477 ,(1990)
J. M. Braganza, P. N. Durrington, J. P. Miller, O. P. Twentyman, Hypertriglyceridaemia and abnormalities of triglyceride catabolism persisting after pancreatitis International Journal of Pancreatology. ,vol. 1, pp. 195- 203 ,(1986) , 10.1007/BF02795245
Stephen B. Hulley, Ray H. Rosenman, Richard D. Bawol, Richard J. Brand, Epidemiology as a Guide to Clinical Decisions New England Journal of Medicine. ,vol. 302, pp. 1383- 1389 ,(1980) , 10.1056/NEJM198006193022503
Ronald M. Krauss, Robert I. Levy, Donald S. Fredrickson, Selective Measurement of Two Lipase Activities in Postheparin Plasma from Normal Subjects and Patients with Hyperlipoproteinemia Journal of Clinical Investigation. ,vol. 54, pp. 1107- 1124 ,(1974) , 10.1172/JCI107855
A. Zambon, J.D. Brunzell, A. Torres, C. Gagne, S. Moorjani, P.J. Lupien, M.R. Hayden, S. Bijvoet, Prevention of raised low-density lipoprotein cholesterol in a patient with familial hypercholesterolaemia and lipoprotein lipase deficiency The Lancet. ,vol. 341, pp. 1119- 1121 ,(1993) , 10.1016/0140-6736(93)93129-O
S P Babirak, P H Iverius, W Y Fujimoto, J D Brunzell, Detection and characterization of the heterozygote state for lipoprotein lipase deficiency Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 9, pp. 326- 334 ,(1989) , 10.1161/01.ATV.9.3.326
Richard Neary, Deepak Bhatnagar, Paul Durrington, Monica Ishola, Sharon Arrol, Michael Mackness, An investigation of the role of lecithin:cholesterol acyltransferase and triglyceride-rich lipoproteins in the metabolism of pre-beta high density lipoproteins. Atherosclerosis. ,vol. 89, pp. 35- 48 ,(1991) , 10.1016/0021-9150(91)90005-N
K.G. Taylor, G. Holdsworth, D.J. Galton, CLOFIBRATE INCREASES LIPOPROTEIN-LIPASE ACTIVITY IN ADIPOSE TISSUE OF HYPERTRIGLYCERIDÆMIC PATIENTS The Lancet. ,vol. 310, pp. 1106- 1107 ,(1977) , 10.1016/S0140-6736(77)90548-7