Ovarian tumors of sex cord-stromal origin

作者: Thierry Philippe

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摘要: Tumors of the stroma (Leydig cells) and/or sex cords (Sertoli represent approximately 8% ovarian tumors and develop from connective tissue (respectively, interstitial nurse ovaries. Because these cells participate in hormonal function, most sex-cord or stromal are able to secrete hormones (estrogens, androgens, corticoids), which explains dysfunctions associated with cancers. Their prognoses difficult establish; some almost always benign cell tumors, Leydig ...), whereas others malignant but more-orless delayed local-regional metastatic relapses. The histological criteria aggressivity so poorly known that it is even propose a dichotomous, benign-malignant histopathological classification. If they do not present clinical "malignity", considered be uncertain prognosis. In this group following might have "malignant" behavior: granulosa androblastomas (or Sertoli-Leydig tumors), annealed tubules, steroid-producing (theca) without any other specification, fibrosarcomas. Surgery important therapeutic modality must as conservative possible preserve reproductive function; can effectively combined chemotherapy.

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