作者: S.W. Grant , G.L. Hickey , N.A. Wisely , E.D. Carlson , R.A. Hartley
DOI: 10.1093/BJA/AEU383
关键词:
摘要: Background Cardiopulmonary exercise testing (CPET) is increasingly used in the preoperative assessment of patients undergoing major surgery. The objective this study was to investigate whether CPET can identify at risk reduced survival after abdominal aortic aneurysm (AAA) repair. Methods Prospectively collected data from consecutive who underwent before elective open or endovascular AAA repair (EVAR) two tertiary vascular centres between January 2007 and October 2012 were analysed. A symptom-limited maximal performed on each patient. Multivariable Cox proportional hazards regression modelling factors associated with survival. Results included 506 a mean age 73.4 (range 44–90). majority (82.6%) men most (64.6%) EVAR. in-hospital mortality 2.6%. median follow-up 26 months. 3-year for zero one sub-threshold value ( V ˙ O 2 AT<10.2 ml kg−1 min−1, peak <15 min−1 E/ C AT>42) 86.4% compared 59.9% three values. Risk independently female sex [hazard ratio (HR)=0.44, 95% confidence interval (CI) 0.22–0.85, P=0.015], diabetes (HR=1.95, CI 1.04–3.69, P=0.039), statins (HR=0.58, 0.38–0.90, P=0.016), haemoglobin g dl−1 (HR=0.84, 0.74–0.95, P=0.006), (HR=1.63, 1.01–2.63, P=0.046), AT>42 (HR=1.68, 1.00–2.80, P=0.049). Conclusions variables are independent predictors cohort 3 years post-procedure. potentially useful adjunct clinical decision-making AAA.