Regulation of L-type Ca2+ channels in the heart: overview of recent advances.
作者： Kaoru Yamaoka , Masaki Kameyama
关键词:
摘要: Regulation of L-type Ca2+ channels is complex, because many factors, such as phosphorylation, divalent cations, and proteins, specified or unspecified, have been shown to affect the channel activities. An additional complication that these factors interact with one another achieve final outcomes. Recent molecular technologies helped shed light on mechanisms governing activity channels. In this review article, three major topics concerning regulation in heart are discussed, i.e. c-AMP dependent role magnesium (Mg2+), phenomenon run-down.
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sci-hub.se 参考文章(159)
J.W. Hell, C.T. Yokoyama, S.T. Wong, C Warner, T.P. Snutch, W.A. Catterall, Differential phosphorylation of two size forms of the neuronal class C L-type calcium channel alpha 1 subunit. Journal of Biological Chemistry. ,vol. 268, pp. 19451- 19457 ,(1993) , 10.1016/S0021-9258(19)36536-6
Dafna Singer-Lahat, Nathan Dascal, Veit Flockerzi, Martin Biel, Franz Hofmann, Ilana Lotan, Cardiac calcium channels expressed in Xenopus oocytes are modulated by dephosphorylation but not by cAMP-dependent phosphorylation. Receptors & Channels. ,vol. 2, pp. 215- 226 ,(1994)
T. F. McDonald, S. Pelzer, W. Trautwein, D. J. Pelzer, Regulation and modulation of calcium channels in cardiac, skeletal, and smooth muscle cells Physiological Reviews. ,vol. 74, pp. 365- 507 ,(1994) , 10.1152/PHYSREV.1994.74.2.365
P. G. Kostyuk, Intracellular perfusion of nerve cells and its effects on membrane currents Physiological Reviews. ,vol. 64, pp. 435- 454 ,(1984) , 10.1152/PHYSREV.1984.64.2.435
Qi-Yi Liu, Robert L. Rosenberg, Stimulation of cardiac L-type calcium channels by extracellular ATP. American Journal of Physiology-cell Physiology. ,vol. 280, ,(2001) , 10.1152/AJPCELL.2001.280.5.C1107
D Günzel, W R Schlue, Sodium‐magnesium antiport in Retzius neurones of the leech Hirudo medicinalis. The Journal of Physiology. ,vol. 491, pp. 595- 608 ,(1996) , 10.1113/JPHYSIOL.1996.SP021242
E. Melloni, F. Salamino, B. Sparatore, The calpain-calpastatin system in mammalian cells: properties and possible functions. Biochimie. ,vol. 74, pp. 217- 223 ,(1992) , 10.1016/0300-9084(92)90120-4
Karl Seydl, Jan -Olof Karlsson, Alfred Dominik, Hermann Gruber, Christoph Romanin, Action of calpastatin in prevention of cardiac L-type Ca2+ channel run-down cannot be mimicked by synthetic calpain inhibitors Pflügers Archiv: European Journal of Physiology. ,vol. 429, pp. 503- 510 ,(1995) , 10.1007/BF00704155
M. Kameyama, J. Hescheler, G. Mieskes, W. Trautwein, The protein-specific phosphatase 1 antagonizes the β-adrenergic increase of the cardiac Ca current Pflügers Archiv: European Journal of Physiology. ,vol. 407, pp. 461- 463 ,(1986) , 10.1007/BF00652635
A Romani, C Marfella, A Scarpa, Regulation of magnesium uptake and release in the heart and in isolated ventricular myocytes. Circulation Research. ,vol. 72, pp. 1139- 1148 ,(1993) , 10.1161/01.RES.72.6.1139