Chemical constituents of Nauclea latifolia and their anti-GST and anti-fungal activities.
作者： Athar Ata , Chibuike C. Udenigwe , Wadim Matochko , Paul Holloway , Michael O. Eze
DOI: 10.1177/1934578X0900400905
关键词:
摘要: The crude ethanolic extract of Nauclea latifolia yielded five known compounds, strictosamide (1), naucleamides A (2), naucleamide F (3), quinovic acid-3-O-beta-rhamnosylpyranoside (4), and acid 3-O-beta-fucosylpyranoside (5). Microbial reactions, using a whole cell culture Rhizopus circinans on compound three analogues, 10-hydroxystrictosamide (6), 10-beta-glucosyloxyvincoside lactam (7) 16,17-dihydro-10-beta-glucosyloxyvincoside (8). Compounds 1-8 were identified with the aid extensive NMR spectral studies. Compound 8 was found to be new metabolite. exhibited different levels anti-GST anti-fungal activities.
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