Chewing tobacco, alcohol, and the risk of erythroplakia.

摘要: Although chewing tobacco, smoking, and alcohol drinking have been suggested as risk factors for oral cancer, no study has examined the relationship between those of erythroplakia, an uncommon but severe premalignant lesion. In this study, we analyzed effects drinking, body mass index, vegetable, fruit, vitamin/iron intake on erythroplakia explored potential interactions in Indian population. A case-control including 100 cases 47,773 controls was conducted, part on-going randomized cancer screening trial Kerala, India. The analysis based data from baseline intervention group, where diagnostic information available. epidemiological collected with interviews conducted by trained health workers. were identified workers visual inspections, then confirmed dentists oncologists who made final diagnosis. odds ratios (OR) their 95% confidence intervals (CIs) calculated logistic regression model using SAS software. adjusted OR 19.8 (95% CI, 9.8–40.0) individuals had ever chewed after controlling age, sex, education, drinking. ever-alcohol-drinkers 3.0 1.6–5.7) smoking. For ever-smokers, 1.6 0.9–2.9). more than additive interaction tobacco low vegetable intake, whereas a multiplicative indicated fruit intake. We concluded that are strong Because CIs terms wide overlapping main effects, only suggested.