High prevalence of airway obstruction and pulmonary emphysema in urothelial (renal pelvis, ureter, and bladder) cancer patients.

作者: Megumi Naka , Saki Shuto , Chisato Konishi , Koichi Maekawa

DOI: 10.1016/J.RESINV.2019.12.004

关键词:

摘要: Abstract Background Cigarette smoking is a major cause of COPD, with patients also presenting complications that stem from other smoking-related diseases, including urothelial cancer. However, the prevalence COPD or airflow obstruction in cancer has not been well studied. Methods We investigated (FEV1/FVC  Results A total 217 were newly diagnosed during study period at our institution. Among all patients, 210 (96.8%) underwent an evaluable lung function test, which 38.6% (81 patients) displayed defined as FEV1/FVC  Conclusions Airflow was identified patients. Age, index (pack-years), and BMI significant risk factors. significantly higher emphysematous score observed subjects than airway alone.

参考文章(36)
Robert P. Young, Fenghai Duan, Caroline Chiles, Raewyn J. Hopkins, Greg D. Gamble, Erin M. Greco, Constantine Gatsonis, Denise Aberle, Airflow Limitation and Histology Shift in the National Lung Screening Trial. The NLST-ACRIN Cohort Substudy American Journal of Respiratory and Critical Care Medicine. ,vol. 192, pp. 1060- 1067 ,(2015) , 10.1164/RCCM.201505-0894OC
Noriaki Takabatake, Sayumi Toriyama, Akira Igarashi, Yoshikane Tokairin, Yasuchika Takeishi, Tsuneo Konta, Sumito Inoue, Shuichi Abe, Yoko Shibata, Isao Kubota, A novel polymorphism in CDC6 is associated with the decline in lung function of ex-smokers in COPD. Biochemical and Biophysical Research Communications. ,vol. 381, pp. 554- 559 ,(2009) , 10.1016/J.BBRC.2009.02.080
TOMOKO BETSUYAKU, MASAHARU NISHIMURA, KIMIHIRO TAKEYABU, MISHIE TANINO, PER VENGE, SHENGYUAN XU, YOSHIKAZU KAWAKAMI, Neutrophil granule proteins in bronchoalveolar lavage fluid from subjects with subclinical emphysema. American Journal of Respiratory and Critical Care Medicine. ,vol. 159, pp. 1985- 1991 ,(1999) , 10.1164/AJRCCM.159.6.9809043
Jette Brommann Kornum, Claus Sværke, Reimar Wernich Thomsen, Peter Lange, Henrik Toft Sørensen, Chronic obstructive pulmonary disease and cancer risk: a Danish nationwide cohort study. Respiratory Medicine. ,vol. 106, pp. 845- 852 ,(2012) , 10.1016/J.RMED.2011.12.009
Tatjana Simic, Ana Savic-Radojevic, Marija Pljesa-Ercegovac, Marija Matic, Jasmina Mimic-Oka, Glutathione S -transferases in kidney and urinary bladder tumors Nature Reviews Urology. ,vol. 6, pp. 281- 289 ,(2009) , 10.1038/NRUROL.2009.49
Daisuke Osaka, Yoko Shibata, Shuichi Abe, Sumito Inoue, Yoshikane Tokairin, Akira Igarashi, Keiko Yamauchi, Tomomi Kimura, Michiko Sato, Hiroyuki Kishi, Noriaki Takabatake, Makoto Sata, Tetsu Watanabe, Tsuneo Konta, Sumio Kawata, Takeo Kato, Isao Kubota, Relationship between habit of cigarette smoking and airflow limitation in healthy Japanese individuals: the Takahata study. Internal Medicine. ,vol. 49, pp. 1489- 1499 ,(2010) , 10.2169/INTERNALMEDICINE.49.3364
Augusto A. Litonjua, Ross Lazarus, David Sparrow, Joshua O. Benditt, Gerard Criner, Barry Make, Fernando J. Martinez, Paul D. Scanlon, Frank C. Sciurba, James P. Utz, John J. Reilly, Edwin K. Silverman, Dawn L. DeMeo, Craig P. Hersh, Eric A. Hoffman, Genetic Determinants of Emphysema Distribution in the National Emphysema Treatment Trial American Journal of Respiratory and Critical Care Medicine. ,vol. 176, pp. 42- 48 ,(2007) , 10.1164/RCCM.200612-1797OC
Roberto de Marco, Simone Accordini, Alessandro Marcon, Isa Cerveri, Josep M. Antó, Thorarinn Gislason, Joachim Heinrich, Christer Janson, Deborah Jarvis, Nino Kuenzli, Bénédicte Leynaert, Jordi Sunyer, Cecilie Svanes, Matthias Wjst, Peter Burney, Risk Factors for Chronic Obstructive Pulmonary Disease in a European Cohort of Young Adults American Journal of Respiratory and Critical Care Medicine. ,vol. 183, pp. 891- 897 ,(2011) , 10.1164/RCCM.201007-1125OC
Norihiro Yamada, Mutsuo Yamaya, Shoji Okinaga, Katsutoshi Nakayama, Kiyohisa Sekizawa, Shigeki Shibahara, Hidetada Sasaki, Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with susceptibility to emphysema. American Journal of Human Genetics. ,vol. 66, pp. 187- 195 ,(2000) , 10.1086/302729
Min-Su Yim, Yun-Sok Ha, Isaac Yi Kim, Seok-Joong Yun, Yung Hyun Choi, Wun-Jae Kim, HMOX1 is an important prognostic indicator of nonmuscle invasive bladder cancer recurrence and progression. The Journal of Urology. ,vol. 185, pp. 701- 705 ,(2011) , 10.1016/J.JURO.2010.09.081