Optimization of antibacterial peptides by genetic algorithms and cheminformatics.
作者： Christopher D. Fjell , Håvard Jenssen , Warren A. Cheung , Robert E. W. Hancock , Artem Cherkasov
DOI: 10.1111/J.1747-0285.2010.01044.X
关键词:
摘要: … peptides with activity of 94% accuracy; active peptides were 47 of the top rated 50 peptides … Here, we report a method of generating candidate peptide sequences using the heuristic …
sci-hub.se 参考文章(26)
David W. Corne, Peter J. Bentley, CREATIVE EVOLUTIONARY SYSTEMS ,(2001)
Shail Patel, Ian Stott, Manmohan Bhakoo, Peter Elliott, Patenting evolved batericidal peptides Creative evolutionary systems. pp. 525- 545 ,(2001) , 10.1016/B978-155860673-9/50062-8
B. Brett Finlay, Robert E. W. Hancock, Can innate immunity be enhanced to treat microbial infections Nature Reviews Microbiology. ,vol. 2, pp. 497- 504 ,(2004) , 10.1038/NRMICRO908
Julian James Faraway, Linear Models with R ,(2014)
Andreas R. Koczulla, Robert Bals, Antimicrobial peptides: current status and therapeutic potential. Drugs. ,vol. 63, pp. 389- 406 ,(2003) , 10.2165/00003495-200363040-00005
Stefan P Niculescu, Artificial neural networks and genetic algorithms in QSAR Journal of Molecular Structure-theochem. ,vol. 622, pp. 71- 83 ,(2003) , 10.1016/S0166-1280(02)00619-X
Tom Solmajer, Jure Zupan, Optimization algorithms and natural computing in drug discovery. Drug Discovery Today: Technologies. ,vol. 1, pp. 247- 252 ,(2004) , 10.1016/J.DDTEC.2004.11.011
Robert E W Hancock, Hans-Georg Sahl, Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nature Biotechnology. ,vol. 24, pp. 1551- 1557 ,(2006) , 10.1038/NBT1267
A. Cherkasov, Inductive Descriptors: 10 Successful Years in QSAR Current Computer - Aided Drug Design. ,vol. 1, pp. 21- 42 ,(2005) , 10.2174/1573409052952288
Stuart B Levy, Bonnie Marshall, Antibacterial resistance worldwide: causes, challenges and responses. Nature Medicine. ,vol. 10, ,(2004) , 10.1038/NM1145