Protective immunity to entamoeba histolytica infection in subjects with antiamoebic antibodies residing in a hyperendemic zone.

作者: Gourdas Choudhuri , Vijay Prakash , Ashok Kumar , Shivendr Kumar Shahi , Mahesh Sharma

DOI: 10.3109/00365549109024306

关键词:

摘要: To investigate the relationship between amoebic gut infection and presence of serum antiamoebic antibodies in a community where amoebiasis is highly endemic, cross-sectional population survey was conducted covering 982 subjects 2 adjacent villages rural India. E. histolytica detected fecal smears 18.1% (88/487) by micro-ELISA 28.7% (251/874) subjects. In 450 whom there no clinical evidence invasive disease or history ingestion drugs previous year from both stool matched samples were obtained, correlation with seropositivity attempted. Seropositivity 80 cyst passers (23.8%) significantly lower than 370 non-cyst (35.1%; p < 0.05). Conversely rate seropositive (19/149; 12.8%) as compared to seronegative (61/301; 23%, wa...

参考文章(22)
H. J. Bos, W. J. Schouten, B. F. J. Oostburg, H. Noordpool, M. Makbin, A seroepidemiological study of amebiasis in Surinam by the enzyme-linked immunosorbent assay (ELISA). American Journal of Tropical Medicine and Hygiene. ,vol. 29, pp. 358- 363 ,(1980) , 10.4269/AJTMH.1980.29.358
P.G. Sargeaunt, J.E. Williams, J.D. Grene, The differentiation of invasive and non-invasive Entamoeba histolytica by isoenzyme electrophoresis Transactions of the Royal Society of Tropical Medicine and Hygiene. ,vol. 72, pp. 519- 521 ,(1978) , 10.1016/0035-9203(78)90174-8
E. H. Sadun, Sydney Cohen, Immunology of Parasitic Infections ,(1982)
R. Nanda, U. Baveja, B.S. Anand, ENTAMOEBA HISTOLYTICA CYST PASSERS: CLINICAL FEATURES AND OUTCOME IN UNTREATED SUBJECTS The Lancet. ,vol. 324, pp. 301- 303 ,(1984) , 10.1016/S0140-6736(84)92682-5
J. I. Ravdin, R. L. Guerrant, A Review of the Parasite Cellular Mechanisms Involved in the Pathogenesis of Amebiasis Clinical Infectious Diseases. ,vol. 4, pp. 1185- 1207 ,(1982) , 10.1093/CLINIDS/4.6.1185
W.P. Stamm, M.J. Ashley, K. Bell, The value of amoebic serology in an area of low endemicity. Transactions of The Royal Society of Tropical Medicine and Hygiene. ,vol. 70, pp. 49- 53 ,(1976) , 10.1016/0035-9203(76)90006-7
Purnima CK Nain, VK Vinayak, Elicitation of protective immunity to Entamoeba histolytica--an experimental study. Immunology and Cell Biology. ,vol. 65, pp. 217- 222 ,(1987) , 10.1038/ICB.1987.24
A Voller, A Bartlett, D E Bidwell, Enzyme immunoassays with special reference to ELISA techniques. Journal of Clinical Pathology. ,vol. 31, pp. 507- 520 ,(1978) , 10.1136/JCP.31.6.507
Keven J. Turner, Leonie Feddema, Elizabeth H. Quinn, Non-Specific Potentiation of IgE by Parasitic Infections in Man International Archives of Allergy and Immunology. ,vol. 58, pp. 232- 236 ,(1979) , 10.1159/000232197