Understanding of Complex Protein Interactions with Respect to Anchorage Independence

作者: Jill M. Tham , Sofie C. Van Huffel , Wanjin Hong

DOI: 10.1007/978-1-4939-2309-0_16

关键词:

摘要: Anchorage-independent growth of cells in soft agar is one the hallmark characteristics cellular transformation and uncontrolled cell growth. It may be considered as most stringent assays for detecting malignant cells. Here, we describe a retroviral infection library small secretory proteins use assay to obtain study novel interacting protein combinations that cause transformation.

参考文章(11)
A D Cox, M M Hisaka, J E Buss, C J Der, Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein. Molecular and Cellular Biology. ,vol. 12, pp. 2606- 2615 ,(1992) , 10.1128/MCB.12.6.2606
Adrienne D. Cox, Channing J. Der, BIOLOGICAL ASSAYS FOR CELLULAR TRANSFORMATION Methods in Enzymology. ,vol. 238, pp. 277- 294 ,(1994) , 10.1016/0076-6879(94)38026-0
Valentin Romanov, S Nikki Davidoff, Adam R Miles, David W Grainger, Bruce K Gale, Benjamin D Brooks, None, A critical comparison of protein microarray fabrication technologies. Analyst. ,vol. 139, pp. 1303- 1326 ,(2014) , 10.1039/C3AN01577G
YI-FEI JI, HUA HUANG, FENG JIANG, RUN-ZHOU NI, MING-BING XIAO, S100 family signaling network and related proteins in pancreatic cancer (Review). International Journal of Molecular Medicine. ,vol. 33, pp. 769- 776 ,(2014) , 10.3892/IJMM.2014.1633
W. S. Pear, G. P. Nolan, M. L. Scott, D. Baltimore, Production of high titer helper-free retroviruses by transient transfection Proceedings of the National Academy of Sciences of the United States of America. ,vol. 90, pp. 8392- 8396 ,(1994) , 10.1073/PNAS.90.18.8392
S Altschula, Warren Gisha, Webb Millerb, E Meyersc, D Lipmana, None, Basic Local Alignment Search Tool Journal of Molecular Biology. ,vol. 215, pp. 403- 410 ,(1990) , 10.1016/S0022-2836(05)80360-2
Jose B Pereira-Leal, Emmanuel D Levy, Christel Kamp, Sarah A Teichmann, Evolution of protein complexes by duplication of homomeric interactions. Genome Biology. ,vol. 8, pp. 1- 12 ,(2007) , 10.1186/GB-2007-8-4-R51
Xiaoyun Sun, Pengyu Hong, Meghana Kulkarni, Young Kwon, Norbert Perrimon, PPIRank - an advanced method for ranking protein-protein interations in TAP/MS data Proteome Science. ,vol. 11, pp. 1- 10 ,(2013) , 10.1186/1477-5956-11-S1-S16
Sofie C Van Huffel, Jill M Tham, XiaoQian Zhang, KohPang Lim, ChunXuan Yang, YikLoo Tan, Felicia Ong, Ian Lee, WanJin Hong, Systematic analysis of secreted proteins reveals synergism between IL6 and other proteins in soft agar growth of MCF10A cells. Cell & Bioscience. ,vol. 1, pp. 13- 13 ,(2011) , 10.1186/2045-3701-1-13