Acute kidney injury based on KDIGO (Kidney Disease Improving Global Outcomes) criteria in patients with elevated baseline serum creatinine undergoing cardiac surgery.

摘要: Introduction: Preoperatively elevated serum creatinine (SCr) is considered an independent risk factor for morbidity and mortality after cardiac surgery. The aim of this study was to apply the Kidney Disease Improving Global Outcomes classification acute kidney injury in a population patients with preoperatively who underwent surgery (coronary artery bypass grafting or valve surgery) evaluate worsening renal function as predictor 30-day mortality. Methods: This single-center retrospective that included from Postoperative Cardiac Surgery Intensive Care Unit Hospital de Base, Sao Jose do Rio Preto Medical School. Demographics, type surgery, laboratory data pre, peri postoperative were obtained prospectively collected database. From January 2003 June 2013, 2,878 either coronary at Base Out those, 918 showed preoperative creatinine, SCr > 1.30 mg/dL men 1.00 women. Five hundred forty nine (60%) undergoing 369 (40%) A Multivariate Cox Proportional Hazard Model (stepwise) used assess relationship between AKI 30 days. Results: studied, 391 (43%) had AKI: 318 (35%) stage 1, 27 (2.9%) 2, 46 (5.0%) 3. Patients every progressive increase EuroSCORE values, ratescardiopulmonary duration, intensive care length stay. Among classified 3, 76% required dialysis 66%. proportional hazards model hazard ratio 4.8 1 patients, 13.5 2 20.8 3 (P<0.001 all). Subgroup analyses similar results. Conclusion: In population, based on criteria powerful surgery).