1-carbacephalosporin antibiotics
作者： John Edwin Munroe
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摘要: 7β-Acylamino-3-alkoxycarbonyl-(and 3-keto)-1-carba(1-dethia)-3-cephem-4-carboxylic acids and derivatives related 3-substituted compounds are provided as antibiotics useful for treating infections in man animals. Pharmaceutical formulations comprising the intermediates a process their preparation provided. Exemplary 7β-[D-(2-phenyl-2-aminoacetyl)amino]-3-methoxycarbonyl-1-carba(1-dethia)-3-cephem-4-carboxylic acid 7β-[2-(2-aminothiazol-4-yl)-2-methoxyimino-acetamido]-3-acetyl-1-carba(1-dethia)-3-cephem-4-carboxylic acid.
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