Cardiac Regeneration with Stem Cells

作者: Beatriz Pelacho , Manuel Mazo , Sheyla Montori , Ana Maria Simon-Yarza , Juan Jose Gavira

DOI: 10.1007/978-1-62703-098-4_5

关键词:

摘要: Cardiovascular diseases (CVD) are the main causes of morbidity and mortality worldwide. A huge effort has been made to improve current standard approaches for treating patients with ischemic heart disease. However, despite greater efficacy new drugs clinical techniques, which have decreased number acute prolonged life chronic ones, classic treatments still not able regenerate diseased heart. For this reason, alternative therapies based on use gene, protein, stem cells developed in combination bioengineering aim only protecting but also repairing damaged All these therapies, especially cell therapy possibility combining biomaterials order reinforce their potential or even create tissues, reviewed chapter.

参考文章(284)
Edorta Santos, Jon Zarate, Gorka Orive, Rosa Ma Hernández, José Luis Pedraz, Biomaterials in Cell Microencapsulation Advances in Experimental Medicine and Biology. ,vol. 670, pp. 5- 21 ,(2010) , 10.1007/978-1-4419-5786-3_2
P. V. Diwan, P. Satheesh Kumar, T. Ram Saini, S. Ramakrishna, Influence of microencapsulation method and peptide loading on formulation of poly(lactide-co-glycolide) insulin nanoparticles. Die Pharmazie. ,vol. 61, pp. 613- 617 ,(2006)
Timothy D. Henry, Cindy L. Grines, Matthew W. Watkins, Nabil Dib, Gerald Barbeau, Randall Moreadith, Tony Andrasfay, Robert L. Engler, Effects of Ad5FGF-4 in patients with angina: an analysis of pooled data from the AGENT-3 and AGENT-4 trials. Journal of the American College of Cardiology. ,vol. 50, pp. 1038- 1046 ,(2007) , 10.1016/J.JACC.2007.06.010
Charles E. Murry, Hans Reinecke, Lil M. Pabon, Regeneration Gaps: Observations on Stem Cells and Cardiac Repair Journal of the American College of Cardiology. ,vol. 47, pp. 1777- 1785 ,(2006) , 10.1016/J.JACC.2006.02.002
Zun Chang Liu, Thomas Ming Swi Chang, Artificial Cell Microencapsulated Stem Cells in Regenerative Medicine, Tissue Engineering and Cell Therapy Advances in Experimental Medicine and Biology. ,vol. 670, pp. 68- 79 ,(2010) , 10.1007/978-1-4419-5786-3_7
Pinak B. Shah, Douglas W. Losordo, Non-viral vectors for gene therapy: clinical trials in cardiovascular disease. Advances in Genetics. ,vol. 54, pp. 339- 361 ,(2005) , 10.1016/S0065-2660(05)54014-8
C.A. Geisberg, D.J. Lenihan, Neuregulin in heart failure Herz. ,vol. 36, pp. 306- 310 ,(2011) , 10.1007/S00059-011-3472-1
Roberto Pola, Leona E. Ling, Marcy Silver, Michael J. Corbley, Marianne Kearney, R. Blake Pepinsky, Renee Shapiro, Frederick R. Taylor, Darren P. Baker, Takayuki Asahara, Jeffrey M. Isner, The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors Nature Medicine. ,vol. 7, pp. 706- 711 ,(2001) , 10.1038/89083
Susan Rainey Daher, Brian H. Johnstone, Donald G. Phinney, Keith L. March, Adipose Stromal/Stem Cells: Basic and Translational Advances: The IFATS Collection Stem Cells. ,vol. 26, pp. 2664- 2665 ,(2008) , 10.1634/STEMCELLS.2008-0927