The immunology of insulin.

摘要: Publisher Summary The chapter discusses in depth the structure of insulin molecules from several vertebrate species, comparing chemical structural features and antigenic characteristics. production anti-insulin antibodies man other species is also presented with an analysis various immunoassay methods for insulin, such as hemagglutination, mouse diaphragm method antibody, using I131-insulin. observations analyses that include resistance produced patient, its association insulin-neutralizing substance blood, fact patient was a non-diabetic who did not become diabetic result circulating are discussed chapter. relationship to etiology, course, treatment diabetes critically reviewed their globulin proteins, antibody animals, properties antibodies. Applications methods, iso-antibodies autoimmunity neutralizable nonneutralizable described