One-year Allograft and Patient Survival in Renal Transplant Recipients Receiving Antiplatelet Therapy at the Time of Transplantation.

作者: D P Hoyer , F H Saner , S Radunz , J W Treckmann , A Bienholz

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摘要: Background: Antiplatelet therapy is common in patients on the waiting list for kidney transplantation. Objective: To evaluate incidence of post-operative bleeding with antiplatelet undergoing transplantation and analyze impact outcome. Methods: We studied all concomitant our center from January 2007 to June 2012. Data were collected by chart review. Univariate multivariate logistic regression Cox proportional hazard model used identify risk factors long-term Results: Of 744 transplant recipients during study period, 161 received oral included study. One-third demonstrated signs bleeding, half which requiring surgical treatment. Coronary artery disease, deceased donor transplantation, dual medication independent bleeding. One-year allograft survival was significantly better non-bleeding group (91.4% vs 75.9%, p=0.023). Multivariable analysis found that recipient age, biopsy-proven rejection graft survival. Recipient age also identified as patient Conclusion: This indicated a high renal under therapy. The associated negative effect underscored need reduce any

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