The Role of Cholinergic and Dopaminergic Interactions in Diseases of the Central Nervous System
作者： M. H. Van Woert
DOI: 10.1007/978-1-4613-2934-3_22
关键词:
摘要: Multiple neurons, each of which release different chemicals at their nerve terminals, synapse in the central nervous system (CNS), and pathological changes metabolism one neurotransmitter can alter transmitters from other neurons circuit. The most thoroughly investigated example this phenomenon is synaptic interaction nigro-striatal dopaminergic with intrastriatal cholinergic cells. Different types abnormalities pathway have been implicated as causally related to movement disorders such Parkinson’s disease, Huntington’s chorea tardive dyskinesias. Dysfunction dopaminergic-cholinergic synapses limbic may be relevant an understanding pathophysiology certain psychiatric disorders. purpose chapter summarize our knowledge interactions abnormal psychoses
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