The mystery behind membrane insertion: a review of the complement membrane attack complex

作者: Charles Bayly-Jones , Doryen Bubeck , Michelle A. Dunstone

DOI: 10.1098/RSTB.2016.0221

关键词:

摘要: The membrane attack complex (MAC) is an important innate immune effector of the complement terminal pathway that forms cytotoxic pores on the surface of microbes. Despite many …

参考文章(101)
Mark J. Walport, Complement. First of two parts. The New England Journal of Medicine. ,vol. 344, pp. 1058- 1066 ,(2001) , 10.1056/NEJM200104053441406
Nicolas S. Merle, Sarah Elizabeth Church, Veronique Fremeaux-Bacchi, Lubka T. Roumenina, Complement System Part I - Molecular Mechanisms of Activation and Regulation. Frontiers in Immunology. ,vol. 6, pp. 262- 262 ,(2015) , 10.3389/FIMMU.2015.00262
R G DiScipio, T E Hugli, The architecture of complement component C9 and poly(C9). Journal of Biological Chemistry. ,vol. 260, pp. 14802- 14809 ,(1985) , 10.1016/S0021-9258(17)38643-X
Nicolas S. Merle, Remi Noe, Lise Halbwachs-Mecarelli, Veronique Fremeaux-Bacchi, Lubka T. Roumenina, Complement System Part II: Role in Immunity. Frontiers in Immunology. ,vol. 6, pp. 257- 257 ,(2015) , 10.3389/FIMMU.2015.00257
F. Niculescu, H. Rus, M.L. Shin, Receptor-independent activation of guanine nucleotide-binding regulatory proteins by terminal complement complexes. Journal of Biological Chemistry. ,vol. 269, pp. 4417- 4423 ,(1994) , 10.1016/S0021-9258(17)41796-0
E R Podack, T F Lint, A F Esser, J G Curd, G R Harriman, A C Wunderlich, A I Braude, The role of C9 in complement-mediated killing of Neisseria. Journal of Immunology. ,vol. 127, pp. 2386- 2390 ,(1981)
V W Hu, B J Wisnieski, A F Esser, E R Podack, The membrane attack mechanism of complement: photolabeling reveals insertion of terminal proteins into target membrane. Journal of Immunology. ,vol. 127, pp. 380- 386 ,(1981)
M L Shin, E W Rauterberg, S Löke, S Schönermark, D Roelcke, G M Hänsch, Homologous species restriction in lysis of human erythrocytes: a membrane-derived protein with C8-binding capacity functions as an inhibitor. Journal of Immunology. ,vol. 136, pp. 1772- 1776 ,(1986)
Carl H. Hammer, Moon L. Shin, David F. Carney, Sang-Ho Kim, Nucleated cell killing by complement: effects of C5b-9 channel size and extracellular Ca2+ on the lytic process. Journal of Immunology. ,vol. 138, pp. 1530- 1536 ,(1987)