Mild Procedural Learning Disturbances in Neuroleptic-Naive Patients With Schizophrenia

摘要: This study investigated whether drug-naive patients with schizophrenia present procedural learning disturbances, given that this function is known to involve the striatum and structural abnormalities of have been described in these patients. Eleven neuroleptic-free schizophrenic were compared 11 healthy control subjects on a visuomotor task (the Mirror Drawing Test). Average performance rate did not differ between two groups. However, lower smoothness consistency which improves from trial trial), would indicate difficulty benefiting past experience perform better current task. Because low has recently found be associated striatal dysfunction, results might premature dysfunction young schizophrenia. severe enough prevent learning.