Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11.

摘要: OBJECTIVE To estimate the potential public health impact of findings Age-Related Eye Disease Study (AREDS) on reducing number persons developing advanced age-related macular degeneration (AMD) during next 5 years in United States. METHODS The AREDS clinical trial provides estimates AMD progression rates and reduction risk when a high-dose nutritional supplement antioxidants zinc is used. These results are applied to US population at risk, people who would potentially avoid if those were take such as that used AREDS. RESULTS An estimated 8 million least 55 old States have monocular or binocular intermediate AMD. They considered be high for whom formulation should considered. Of these people, 1.3 develop no treatment given reduce their risk. If all received supplements AREDS, more than 300,000 (95% confidence interval, 158,000-487,000) them any associated vision loss years. CONCLUSION suggested by results, considerable