Experimental Manipulation of Midfacial Growth: A Synthesis of Five Years of Research at the Iowa Maxillofacial Growth Laboratory

摘要: The purpose of this report is to summarize results and generalizations animal experimentation conducted at the Iowa Maxillofacial Growth Laboratory, comment on directions future activity. Since 1965, laboratory has functioned as part a hospital-based interdisciplinary research project aimed improvement cleft palate habilitative techniques. maintains organizational affiliation with department otolaryngology maxillofacial surgery in College Medicine, orthodontics Dentistry. Research emphasis been studies high potential for providing information relatively rapid clinical application. long-range goal elucidation control mechanisms that influence growth complex. A more immediate identification surgical variables used repairs might interfere postsurgical face. Ultimately, we hope develop ways avoid or compensate growthinhibiting variables. Achievement would mean repair could be done humans soon after birth was medically feasible, delay until second third postnatal year no longer necessary. Other goals led involvement dental development dogs, role nasal septal apparatus dogs rats. Most work using beagle but recent findings suggest rats can