Mast cells are responsible for the lack of anti-inflammatory effects of morphine in CBA mice
作者： Elzbieta Stankiewicz , Ewa Wypasek , Barbara Plytycz
DOI: 10.1080/09629350400008778
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摘要: BACKGROUND and aim : Morphine co-injection has anti-inflammatory effects on zymosan-induced peritonitis in several strains of mice except that CBA. As peritoneal mast cells (pMCs) are much more numerous CBA than SWISS mice, the role pMCs morphine-modulated zymosan is compared males. Methods: were treated vitro with morphine or C48u80 for comparison histamine release. In vivo accumulation leukocytes exudate recorded after intraperitoneal injection morphine, zymosan, plus morphine. Results conclusion induces release by from but not mice. morphine-induced stronger Corollary, antiinflammatory reversed its pro-inflammatory action through pMCs.
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A Kuriu, K Jozaki, Y Kitamura, A Yamatodani, N Waki, S Tarui, S Adachi, Proliferative potential of murine peritoneal mast cells after degranulation induced by compound 48/80, substance P, tetradecanoylphorbol acetate, or calcium ionophore A23187. Journal of Immunology. ,vol. 145, pp. 4252- 4256 ,(1990)
Jamila Louahed, Catherine Godfraind, Richard Grencis, Anne Vink, Guy Warnier, Helen Faulkner, Jean-Christophe Renauld, Intraepithelial Infiltration by Mast Cells with Both Connective Tissue-Type and Mucosal-Type Characteristics in Gut, Trachea, and Kidneys of IL-9 Transgenic Mice Journal of Immunology. ,vol. 160, pp. 3989- 3996 ,(1998)
M. Chadzinska, A. Scislowska-Czarnecka, B. Plytycz, Inhibitory effects of morphine on some inflammation-related parameters in the goldfish Carassius auratusL. Fish & Shellfish Immunology. ,vol. 10, pp. 531- 542 ,(2000) , 10.1006/FSIM.2000.0270
Barbara Plytycz, Joanna Natorska, Morphine attenuates pain and prevents inflammation in experimental peritonitis Trends in Immunology. ,vol. 23, pp. 345- 346 ,(2002) , 10.1016/S1471-4906(02)02257-3
Jeanine L. Bussiere, Martin W. Adler, Thomas J. Rogers, Toby K. Eisenstein, Differential effects of morphine and naltrexone on the antibody response in various mouse strains. Immunopharmacology and Immunotoxicology. ,vol. 14, pp. 657- 673 ,(1992) , 10.3109/08923979209005416
Joanna Natorska, Barbara Plytycz, Strain-specific differences in modulatory effects of morphine on peritoneal inflammation in mice. Folia Biologica. ,vol. 53, pp. 189- 195 ,(2005) , 10.3409/173491605775142701
M CHADZINSKA, Differential migratory properties of mouse, fish, and frog leukocytes treated with agonists of opioid receptors. Developmental and Comparative Immunology. ,vol. 28, pp. 949- 958 ,(2004) , 10.1016/J.DCI.2004.02.003
E. Kolaczkowska, R. Seljelid, B. Plytycz, Critical role of mast cells in morphine-mediated impairment of zymosan-induced peritonitis in mice. Inflammation Research. ,vol. 50, pp. 415- 421 ,(2001) , 10.1007/PL00000264
F. Levi-Schaffer, D. Slovik, L. Armetti, D. Pickholtz, E. Touitou, Activation and inhibition of mast cells degranulation affect their morphometric parameters. Life Sciences. ,vol. 66, ,(2000) , 10.1016/S0024-3205(00)00538-5
J. W. Verbsky, P. K. McAllister, D. G. Malone, Mast cell activation in human synovium explants by calcium ionophore A23187, compound 48/80, and rabbit IgG anti-human IgE, but not morphine sulfate Inflammation Research. ,vol. 45, pp. 35- 41 ,(1996) , 10.1007/BF02263503