Automated identification of peptides
作者： Robert Reid Townsend , Andrew William Robinson
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摘要: A fully automated, user-independent method is described for computer-mediated interpretation of data derived by mass spectrometry an experimental peptide to identify and characterize a corresponding sequence in database. The identifies the if it present database, without need skilled observer choose from amongst list possible matches. By using automated back-read process, can uniquely database based on single matching sequence. also permits mapping spectral sequences or nucleotide databases unambiguous identification exons; determining correct reading frame; identifying artefacts errors sequences; mutations polymorphisms; post-translational modifications; exon-intron boundaries.
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