Mechanistic insights into the interactions of magnetic nanoparticles with bovine serum albumin in presence of surfactants

作者: Delina Joseph , Shilpee Sachar , Nand Kishore , Sudeshna Chandra

DOI: 10.1016/J.COLSURFB.2015.08.022

关键词:

摘要: This work reports the physicochemical parameters and nature of association between magnetic nanoparticles bovine serum albumin (BSA) in presence cationic anionic surfactants. Magnetic iron oxide (MNPs) are first synthesized using chemical co-precipitation method subsequently characterized by FTIR, XRD, DLS, TEM Zeta potential. The bare then coated with BSA their interactions studied fluorescence spectroscopy, dynamic light scattering circular dichroism techniques. spectroscopic investigation sheds into various aspects binding size variation during molecular MNPs absence Isothermal titration calorimetry was used to probe thermodynamic systems. MNPs-BSA system found be more stable surfactant. study provides valuable mechanistic insights taking place at interface which further helps designing a colloidal

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