Functional brain network topology across the menstrual cycle is sex hormone dependent and correlates with the individual well-being

摘要: Abstract The menstrual cycle is known to influence the behaviour. neuronal bases of this phenomenon are poorly understood. We hypothesized that hormones, might affect large-scale organization brain functional networks and that, in turn, such changes have behavioural correlates terms affective state. To test our hypothesis, we took advantage magnetoencephalography investigate topology early follicular, ovulatory luteal phases, twenty-four naturally-cycling women without signs anxiety and/or depression. show alpha band betweenness centrality (BC) right posterior cingulate gyrus (PCG) during phase increased rise predicted by levels estradiol. also demonstrate increase BC related improved subjective well-being correlated estradiol levels. topological PCG could implications reproductive psychology.