Modafinil reduces microsleep during partial sleep deprivation in depressed patients

作者: M. Hatzinger , E. Holsboer-Trachsler , J. Beck , U. Hemmeter , S. Brand

DOI: 10.1016/J.JPSYCHIRES.2010.01.008

关键词:

摘要: Sleep deprivation (SD) can induce a prompt decrease in depressive symptoms within 24h. Following the recovery night, however, relapse into depression occurs most patients. Recovery sleep, naps and even very short episodes of sleep (microsleep; MS) during SD have been shown to provoke rapid depression. This study tested hypothesis that modafinil reduces MS stabilizes treatment response PSD compared placebo.

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