19 new steroidal saponins from Allium plants: isolation, structural elucidation and effect on blood coagulability.

摘要: Allium plants have been grown for many centuries their characteristic, pungent flavor and medicinal properties. In ancient China, Egypt, India, (especially onion garlic) are highly prized as foodstuffs. With regard to the chemical constituents in plants, early investigations focused on volatile compounds (sulfur-containing compounds) products, (involatile) precursors, biochemical basis of production.1 Since tremendous improvements over last two decades techniques isolation, separation, analysis complex structures achieved, a variety steroidal saponins isolated from spp. such A. sativum,2 ampeloprasum,3 vineale,4 cepa 5. The important biological activities increasing interest recently illustrated by potential value antifungal agents 2,3 anti-thrombotic agents.6