Comparative structural analysis of human Nav1.1 and Nav1.5 reveals mutational hotspots for sodium channelopathies.
作者： Nieng Yan , Xiaojing Pan , Yanyu Zhao , Zhangqiang Li , Jianlin Lei
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摘要: Among the nine subtypes of human voltage-gated sodium (Na v ) channels, the brain and cardiac isoforms, Na v 1.1 and Na v 1.5, each carry more than 400 missense mutations …
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