Molecular Confirmation of Hepatitis A Virus from Well Water: Epidemiology and Public Health Implications
作者： Gaston De Serres , Theresa L. Cromeans , Benoit Levesque , Nicole Brassard , Christine Barthe
DOI: 10.1086/314565
关键词:
摘要: An outbreak of hepatitis A in a rural river-island community was found to be associated with consumption contaminated well water. Specimens from case-patients, the implicated well, and cesspool suspected source contamination were all positive for virus (HAV) RNA by immunocapture reverse-transcription polymerase chain reaction. All isolates identical over about 400 bases two capsid-encoding regions genome, identifying transmission. Other wells up 60 m also contained HAV RNA. In addition, detected 6 months after initial contamination, when fecal coliform bacteria no longer present. These findings demonstrate utility viral detection techniques evaluate ground
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