作者: Lindsay E. Nicolle , Janet Bjornson , Godfrey K. M. Harding , J. A. MacDonell
DOI: 10.1056/NEJM198312083092304
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摘要: Over a two-year period we obtained monthly urine samples from all noncatheterized male residents on two geriatric wards to determine the occurrence and optimal management of bacteriuria in this population. Among 88 men prevalence was 33 per cent, incidence 45 infections 100 patients year. Outcomes after single-dose therapy for asymptomatic with 43 courses trimethoprim/sulfamethoxazole 23 tobramycin included 15 cures, 40 relapses, 11 treatment failures. Thirty-six who had relapse or whom failed were randomly assigned receive eradicate no therapy. All 20 received remained bacteriuric. The 16 fewer months randomization, but at end study only one free bacteriuria. Mortality infectious morbidity randomization similar groups. These data suggest that is common elderly institutionalized neither necessary nor effective.