作者: Travis D. Richardson , Stephen J. Pineda , K Brandon Strenge , Tim A. Van Fleet , Margaret MacGregor
DOI: 10.1097/BRS.0B013E318169574D
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摘要: STUDY DESIGN: A retrospective study measuring postoperative serum titanium levels in patients with alloy spinal instrumentation. OBJECTIVE: To determine after instrumented arthrodesis implants composed of and to identify potential factors responsible for any increase ion levels. SUMMARY OF BACKGROUND DATA: Previous studies have documented localized metal debris the tissues surrounding Systemic distribution has also been demonstrated by elevated implants; however, no exist on impact instrumentation characteristics METHODS: Serum concentrations were measured 30 at a mean 26 months surgery compared control group without metallic implants. Comparisons made regarding respect specific such as number pedicle screws used, presence cross connectors or interbody devices. RESULTS.: significantly higher (mean, 2.6 microg/L) when controls 0.71 microg/L). Subjects who underwent an only one segment had decreased those fused 2 more segments 2.3 vs. 3.1 4 less constructs 6 8 3.35 microg/L); both these findings not statistically significant. Patients slightly increased level 2.7 2.44 this finding was devices significant elevation 3.3 1.98 CONCLUSION: Significantly observed subjects controls. Continued research is necessary examine relationship between Ti regards