Mobile DNA: an Introduction

摘要: The once revolutionary idea that genomes contain segments of mobile DNA was actually first conceptualized before the discovery structure DNA. Mobile suggested by McClintock when she described "controlling elements" in maize. A notable feature work presented this volume is our understanding many these recombination reactions has moved to biochemical and structural level. It appropriate begin a discussion site-specific considering conservative recombination. Genetic studies 1950s provided one earliest examples genome modification Transposition reaction mediates movement discrete between nonhomologous sites. These are variously called insertion sequences, transposons, transposable elements. There two large classes elements: (i) those which actual substrate for (ii) RNA Several systems mediate alternate expression multiple alleles gene moving alternative copies or from ‘‘silent’’ position an active ‘‘expression site’’. continued study will lead us more DNAs identify understand, further investigation into help understand function genomes.