Proteins of purified Epstein-Barr virus
作者： E. Johannsen , M. Luftig , M. R. Chase , S. Weicksel , E. Cahir-McFarland
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摘要: Mature Epstein-Barr virus (EBV) was purified from the culture medium of infected lymphocytes made functionally conditional for Zta activation lytic replication by an in-frame fusion with a mutant estrogen receptor. Proteins in preparations were separated gradient gel electrophoresis and trypsin-digested; peptides then analyzed tandem hydrophobic chromatography, MS sequencing, scans. Potential matched EBV human gene ORFs. mostly composed homologues proteins previously found herpes virion. However, to simplex capsid-associated or tegument components UL7 (BBRF2), UL14 (BGLF3), BFRF1 not significantly detected. Instead, probable included γ-herpesvirus-encoded BLRF2, BRRF2, BDLF2 BKRF4 proteins. Actin also major protein, cofilin, tubulin, heat shock protein 90, 70 substantial components. envelope glycoprotein gp350 highly abundant, followed gH, intact furin-cleaved gB, gM, gp42, gL, gp78, gp150, gN. BILF1 (gp64) associated latent infection detected virions.
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sci-hub.se 参考文章(35)
L. M. Hutt-Fletcher, C. M. Lake, Two Epstein-Barr Virus Glycoprotein Complexes Current Topics in Microbiology and Immunology. ,vol. 258, pp. 51- 64 ,(2001) , 10.1007/978-3-642-56515-1_4
U A Gompels, M A Craxton, R W Honess, Conservation of gene organization in the lymphotropic herpesviruses herpesvirus Saimiri and Epstein-Barr virus. Journal of Virology. ,vol. 62, pp. 757- 767 ,(1988) , 10.1128/JVI.62.3.757-767.1988
K R Cameron, T Stamminger, M Craxton, W Bodemer, R W Honess, B Fleckenstein, The 160,000-Mr virion protein encoded at the right end of the herpesvirus saimiri genome is homologous to the 140,000-Mr membrane antigen encoded at the left end of the Epstein-Barr virus genome. Journal of Virology. ,vol. 61, pp. 2063- 2070 ,(1987) , 10.1128/JVI.61.7.2063-2070.1987
M Gong, E Kieff, Intracellular trafficking of two major Epstein-Barr virus glycoproteins, gp350/220 and gp110. Journal of Virology. ,vol. 64, pp. 1507- 1516 ,(1990) , 10.1128/JVI.64.4.1507-1516.1990
C J Baldick, T Shenk, Proteins associated with purified human cytomegalovirus particles. Journal of Virology. ,vol. 70, pp. 6097- 6105 ,(1996) , 10.1128/JVI.70.9.6097-6105.1996
Nell S. Lurain, Gregory T. Spear, Mohammed Saifuddin, Charles J. Parker, Gregory H. Payne, Mahmood Ghassemi, Host cell-derived complement control proteins CD55 and CD59 are incorporated into the virions of two unrelated enveloped viruses. Human T cell leukemia/lymphoma virus type I (HTLV-I) and human cytomegalovirus (HCMV). Journal of Immunology. ,vol. 155, pp. 4376- 4381 ,(1995)
T R Serio, A Angeloni, J L Kolman, L Gradoville, R Sun, D A Katz, W Van Grunsven, J Middeldorp, G Miller, Two 21-kilodalton components of the Epstein-Barr virus capsid antigen complex and their relationship to ZEBRA-associated protein p21 (ZAP21). Journal of Virology. ,vol. 70, pp. 8047- 8054 ,(1996) , 10.1128/JVI.70.11.8047-8054.1996
Andrew J Davison, Evolution of the herpesviruses Veterinary Microbiology. ,vol. 86, pp. 69- 88 ,(2002) , 10.1016/S0378-1135(01)00492-8
Keith M. Haan, Suk Kyeong Lee, Richard Longnecker, Different functional domains in the cytoplasmic tail of glycoprotein B are involved in Epstein-Barr virus-induced membrane fusion. Virology. ,vol. 290, pp. 106- 114 ,(2001) , 10.1006/VIRO.2001.1141
Andrew J Davison, Derrick J Dargan, Nigel D Stow, None, Fundamental and accessory systems in herpesviruses Antiviral Research. ,vol. 56, pp. 1- 11 ,(2002) , 10.1016/S0166-3542(02)00107-9