Abstract P261: Skeletal Muscle Density: A Novel Risk Factor for Hypertension in Aging African Ancestry Men

摘要: Background: Intramuscular fat is greater in African compared with European ancestry men and now recognized as a major risk factor for cardio-metabolic diseases, independent of general obesity. However, prospective studies examining health consequences this important ectopic depot are lacking, particularly high-risk populations. Therefore, we sought to determine if change skeletal muscle density, measure intramuscular fat, predicts subsequent development hypertension men. Methods: We measured at two time points calf density (MD; mg/cm3) using computed tomography 1504 Afro-Caribbean aged 40-92 years (mean, 59 years), who were recruited without regard their status. Hypertension was defined having systolic blood pressure 140 mm Hg or greater, diastolic 90 taking antihypertensive medications. Logistic regression used estimate the association between change...