In Situ Synthesis of Robust Conductive Cellulose/Polypyrrole Composite Aerogels and Their Potential Application in Nerve Regeneration

摘要: Nanostructured conductive polymers can offer analogous environments for extracellular matrix and induce cellular responses by electric stimulation, however, such materials often lack mechanical strength tend to collapse under small stresses. We prepared electrically nanoporous coating cellulose gels (NCG) with polypyrrole (PPy) nanoparticles, which were synthesized in situ from pyrrole monomers supplied as vapor. The resulting NCG/PPy composite hydrogels converted aerogels drying supercritical CO2, giving a density of 0.41–0.53 g cm−3, nitrogen adsorption surface areas 264–303 m2 g−1, high strength. exhibited an electrical conductivity up 0.08 S cm−1. In vitro studies showed that the incorporation PPy into NCG enhances adhesion proliferation PC12 cells. Electrical stimulation demonstrated cells attached extended longer neurites when cultured on DBSA dopant. These are promising candidates applications in nerve regeneration, carbon capture, catalyst supports, many others.