Controlling covalent functionalization of graphene oxide membranes to improve enantioseparation performances

摘要: Abstract At present, the separation of racemates is still a great challenge due to their similarity in chemical structures and physicochemical properties. Here, we proposed new strategy improve enantioseparation performances graphene oxide (GO) based membranes via controlling degree functionalization (DF) GO by aid an epoxide ring-opening reaction with carboxyl-terminated ionic liquid (IL-COOH) as spacer, followed amidation l-glutamic acid (GO-IL-Glu) chiral selectors. Results show that: i) these are superior enantioselectivity 1–3 orders magnitude higher flux than traditional membranes; ii) compared modified complex polypeptides our previous work, they afford ca. 40–80% increase enantioselectivities order fluxes. Herein, IL-COOH groups can not only serve which propitious expanding interlayer spacing GO-IL-Glu nanosheets, thereby achieving high throughput enantiomers, but also function active site grafting amount selectors (l-Glu), helpful for enhancing enantioselectivities. In particular, compromised improved such on contrary, it has increase. Our findings suggest that used this i.e., combining more wider spacing, could provide opportunities simultaneously facilitating high-flux high-selectivity potential application many enantio- bio-separations.