Nanoscale Piezoelectric Properties of Self-Assembled Fmoc-FF Peptide Fibrous Networks

作者: Kate Ryan , Jason Beirne , Gareth Redmond , Jason I. Kilpatrick , Jill Guyonnet

DOI: 10.1021/ACSAMI.5B01251

关键词:

摘要: Fibrous peptide networks, such as the structural framework of self-assembled fluorenylmethyloxycarbonyl diphenylalanine (Fmoc–FF) nanofibrils, have mechanical properties that could successfully mimic natural tissues, making them promising materials for tissue engineering scaffolds. These nanomaterials been determined to exhibit shear piezoelectricity using piezoresponse force microscopy, previously reported FF nanotubes. Structural analyses Fmoc–FF nanofibrils suggest observed piezoelectric response may result from noncentrosymmetric nature an underlying β-sheet topology. The fibrous networks is advantageous a range biomedical applications where electrical or stimuli are required.

参考文章(53)
Suzi Jarvis, Anika Mostaert, The Functional Fold : Amyloid Structures in Nature Pan Stanford Publishing. ,(2012) , 10.1201/B12776
Nina Berova, Robert W. Woody, 香爾 中西, Circular Dichroism: Principles and Applications ,(1994)
D. Denning, M. V. Paukshto, S. Habelitz, B. J. Rodriguez, Piezoelectric properties of aligned collagen membranes. Journal of Biomedical Materials Research Part B. ,vol. 102, pp. 284- 292 ,(2014) , 10.1002/JBM.B.33006
Tom McDonald, Alison Patrick, Richard Williams, Brian G. Cousins, Rein V. Ulijn, Bio‐Responsive Hydrogels for Biomedical Applications Biomedical applications of electroactive polymer actuators. pp. 43- 59 ,(2009) , 10.1002/9780470744697.CH2
Samuel Krimm, Jagdeesh Bandekar, Vibrational spectroscopy and conformation of peptides, polypeptides, and proteins. Advances in Protein Chemistry. ,vol. 38, pp. 181- 364 ,(1986) , 10.1016/S0065-3233(08)60528-8
Scott Fleming, Pim W. J. M. Frederix, Iván Ramos Sasselli, Neil T. Hunt, Rein V. Ulijn, Tell Tuttle, Assessing the Utility of Infrared Spectroscopy as a Structural Diagnostic Tool for β-Sheets in Self-Assembling Aromatic Peptide Amphiphiles Langmuir. ,vol. 29, pp. 9510- 9515 ,(2013) , 10.1021/LA400994V
X. Gao, H. Matsui, Peptide-Based Nanotubes and Their Applications in Bionanotechnology. Advanced Materials. ,vol. 17, pp. 2037- 2050 ,(2005) , 10.1002/ADMA.200401849
Lihi Adler-Abramovich, Meital Reches, Victoria L. Sedman, Stephanie Allen, Saul J. B. Tendler, Ehud Gazit, Thermal and Chemical Stability of Diphenylalanine Peptide Nanotubes: Implications for Nanotechnological Applications Langmuir. ,vol. 22, pp. 1313- 1320 ,(2006) , 10.1021/LA052409D