Hemodynamics in the Circle of Willis with Internal Carotid Artery Stenosis under Cervical Rotatory Manipulation: A Finite Element Analysis

摘要: Background The circle of Willis (CoW) plays an important role in cerebral collateral circulation. hemodynamics changes the CoW have usually been associated with internal carotid artery (ICA) stenosis, but whether rotatory manipulation will affect it remains unknown. Material and methods In this study we attempted to analyze influence on models or without ICA stenosis by means finite element analysis. For purpose, was reasonably simplified a fluid-solid coupling 3D model created using MIMICS10.0 ANSYS14.5. healthy (without stenosis) diseased (ratios include 15%, 30%, 45%, 60%, 70%, 80%, 90%) situations were simulated. A remote displacement 60° applied at distal (the right chosen here) imitate manipulation. Blood flow then monitored anterior communicating (ACoA) posterior arteries (PCoA). Results Before conduction manipulation, blood changed significantly only when ratio increased more than situation did not significant difference after application except ration 90%. Conclusions result suggests that does obvious is less 90%, kind suggested be safe technique most clinical applications.