Treatment of refractory hemorrhage with Factor XIII in a patient with hemophilia A with inhibitor.
作者： Christopher Ng , Christopher C. Silliman , Gabrielle Pearl , Whitney Smith , Marilyn Manco-Johnson
DOI: 10.1002/PBC.24478
关键词:
摘要: An 11-year-old male with hemophilia A and a known high-titer Factor VIII inhibitor was admitted retroperitoneal hemorrhage. The patient receiving infusions of recombinant activated VII (rFVIIa) for recent elbow hemorrhage when bleeding commenced. Despite increased dosing rFVIIa dose prothrombin complex concentrate (aPCC), he continued to required several blood transfusions. XIII administered 1 hour after the demonstrated cessation normalization clot strength. may act as an adjuvant in effective stabilization patients inhibitory antibodies. Pediatr Blood Cancer 2013; 60: E23–E25. © 2013 Wiley Periodicals, Inc.
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