The HLA system in hematopoietic stem cell transplantation
作者： Dominique Charron , Effie Petersdorf
DOI: 10.1016/B978-0-12-416004-0.00002-1
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摘要: Abstract The human major histocompatibility complex (MHC) is residence to the leukocyte antigen (HLA) genes that play a fundamental role in acceptance of transplanted tissues. ubiquitous expression HLA antigens on nucleated cells key feature their function both health and disease. In this chapter, content, organization, diversity within MHC are discussed, clinical implications genetic polymorphism risks graft-versus-host disease (GVHD) hematopoietic stem cell transplantation (HSCT) summarized.
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