Characterization of pediatric Wilms' tumor using Raman and fluorescence spectroscopies.
作者： Chad A. Lieber , Mustafa H. Kabeer
DOI: 10.1016/J.JPEDSURG.2009.07.030
关键词:
摘要: Purpose: Raman spectroscopy has been successfully demonstrated as an effective tool for tissue characterization and diagnosis, but nearly all studies have interrogated adult tissues diseases. In this study, we demonstrate the application of its background autofluorescence pediatric Wilms' tumor diagnosis. Methods: Eight tumors were measured in along with matched normal kidney 6 cases. Spectral comparisons drawn, diagnostic use was assessed using both spectral features well inherent fluorescence. Results: The fluorescent spectra able to discriminate from 81% sensitivity 100% specificity. obtained 93% Conclusions: This pilot study shows that provide discriminating kidney. These techniques may be used individually or tandem develop a real-time intraoperative screening device.
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sci-hub.se 参考文章(21)
M. Linet, J. G. Gurney, L. A. G. Ries, M. A. Smith, T. Tamra, G. R. Bunin, J. L. Young, Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995. Cancer incidence and survival among children and adolescents: United States SEER Program 1975-1995.. ,(1999)
Maria Consuelo, Hart Prieto, Pavel Matousek, Michael Towrie, Anthony William Parker, Mark Wright, Alistair William Ritchie, Nicholas Stone, None, Use of picosecond Kerr-gated Raman spectroscopy to suppress signals from both surface and deep layers in bladder and prostate tissue Journal of Biomedical Optics. ,vol. 10, pp. 044006- ,(2005) , 10.1117/1.1991848
Anita Mahadevan-Jansen, Rebecca R Richards-Kortum, Raman spectroscopy for the detection of cancers and precancers Journal of Biomedical Optics. ,vol. 1, pp. 31- 70 ,(1996) , 10.1117/12.227815
A. Scholtz, Excitation of cold cavity modes in a coupling-modulated CO<inf>2</inf>laser IEEE Journal of Quantum Electronics. ,vol. 11, pp. 791- 793 ,(1975) , 10.1109/JQE.1975.1068985
Stavros G. Demos, Regina Gandour-Edwards, Rajen Ramsamooj, Ralph deVere White, Near-infrared autofluorescence imaging for detection of cancer. Journal of Biomedical Optics. ,vol. 9, pp. 587- 592 ,(2004) , 10.1117/1.1688812
Hale Wills, Rachel Kast, Cory Stewart, Raja Rabah, Abhilash Pandya, Janet Poulik, Greg Auner, Michael D. Klein, Raman spectroscopy detects and distinguishes neuroblastoma and related tissues in fresh and (banked) frozen specimens Journal of Pediatric Surgery. ,vol. 44, pp. 386- 391 ,(2009) , 10.1016/J.JPEDSURG.2008.10.095
Chad A. Lieber, Shiro Urayama, Nazir Rahim, Raymond Tu, Ramez Saroufeem, Boris Reubner, Stavros G. Demos, Multimodal near infrared spectral imaging as an exploratory tool for dysplastic esophageal lesion identification Optics Express. ,vol. 14, pp. 2211- 2219 ,(2006) , 10.1364/OE.14.002211
Raja Rabah, Rachel Weber, Gulay K. Serhatkulu, Alex Cao, Houbei Dai, Abhilash Pandya, Ratna Naik, Gregory Auner, Janet Poulik, Michael Klein, Diagnosis of neuroblastoma and ganglioneuroma using Raman spectroscopy Journal of Pediatric Surgery. ,vol. 43, pp. 171- 176 ,(2008) , 10.1016/J.JPEDSURG.2007.09.040
Ivan S. Lee, Si Nguyen, Allan M. Shanberg, Pediatric Articles: Needle Tract Seeding After Percutaneous Biopsy of Wilms Tumor Journal of Urology. ,vol. 153, pp. 1074- 1076 ,(1995) , 10.1016/S0022-5347(01)67646-8
Chad A. Lieber, Elizabeth M. Kanter, Anita Mahadevan-Jansen, Comparison of Raman spectrograph throughput using two commercial systems: transmissive versus reflective. Applied Spectroscopy. ,vol. 62, pp. 575- 582 ,(2008) , 10.1366/000370208784344488