Effects of Epidural Bupivacaine After Thoracotomy

摘要: Background and Objectives. Combinations of bupivacaine fentanyl are popular for postoperative epidural analgesia. However, there little data from which to select a rational dose bupivacaine. The study examined the effects increasing amounts on analgesia, consumption, side after thoracotomy. Methods. Twenty-four patients were randomized in double-blind manner receive intra- infusions either saline, 0.01% bupivacaine, 0.05% or 0.1% at 10 mL/h. All received standardized combined (120 mg lidocaine 1.5 μg/kg fentanyl) general anesthesia. Further analgesia was provided with patient-controlled (PCEA) only. Results. There no differences between groups visual analog scale (VAS) pain scores rest cough, but 5 mg/h better during physiotherapy (P Conclusions. results demonstrate improved significant opioid sparing when doses used. incidence orthostasis may be increased use mg/h. Thus, (.05% mL/h) decreased requirements, did not have detectable hemodynamic effects.