The acute phase response of acid soluble glycoprotein, alpha(1)-acid glycoprotein, ceruloplasmin, haptoglobin and C-reactive protein, in the pig.
作者： P.D. Eckersall , P.K. Saini , C. McComb
DOI: 10.1016/0165-2427(95)05527-4
关键词:
摘要: The acute phase serum protein response to infection, inflammation or trauma has been identified in a number of species and consists alterations the concentrations several proteins. It is known that profile stimulation differs between species. In pig, individual proteins have as association with infection pathological lesions. this investigation, turpentine injection was used stimulate sterile inflammatory lesion pigs so relative changes could be determined most appropriate markers inflammation. mean concentration acid soluble glycoprotein fraction showed two-fold increase peak 2 days after treatment. alpha(1)-acid fluctuated during period following little difference from control animals. ceruloplasmin increased by 40% 4th day haptoglobin more than reaching on 2nd C-reactive level eight-fold injection. are likely best for identification lesions pigs.
elsevier.com
sci-hub.se 参考文章(17)
G. Grieninger, P.B. Sehgal, G. Tosato, Regulation of the acute phase and immune responses New York, NY (USA); The New York Academy of Sciences. ,(1989)
J.G. Conner, P.D. Eckersall, A. Wiseman, T.C. Aitchison, T.A. Douglas, Bovine acute phase response following turpentine injection. Research in Veterinary Science. ,vol. 44, pp. 82- 88 ,(1988) , 10.1016/0034-5288(88)90018-5
D J Schaeffer, D P Bane, T E Eurell, W F Hall, Serum haptoglobin concentration as an indicator of weight gain in pigs. Canadian Journal of Veterinary Research-revue Canadienne De Recherche Veterinaire. ,vol. 56, pp. 6- 9 ,(1992)
H Itoh, K Tamura, K Kidoguchi, Y Motoi, M Izumi, Y Funayama, The influence of age and health status on the serum alpha 1-acid glycoprotein level of conventional and specific pathogen-free pigs. Canadian Journal of Veterinary Research-revue Canadienne De Recherche Veterinaire. ,vol. 57, pp. 74- 78 ,(1993)
J. T. Whicher, C. I. Westacott, The acute phase response Biochemistry of Inflammation. pp. 243- 269 ,(1992) , 10.1007/978-94-011-2996-1_13
Biochemistry of inflammation Kluwer Academic Publishers. ,(1992) , 10.1007/978-94-011-2996-1
A. R. W. Elbers, I. J. R. Visser, J. Odink, J. F. M. Smeets, Changes in haematological and clinicochemical profiles in blood of apparently healthy slaughter pigs, collected at the farm and at slaughter, in relation to the severity of pathological-anatomical lesions. Veterinary Quarterly. ,vol. 13, pp. 1- 9 ,(1991) , 10.1080/01652176.1991.9694278
H. Nagahata, K. Taguchi, H. Noda, Preliminary studies on the acid soluble glycoproteins in serum and their diagnostic value for acute inflammatory diseases in cattle. Veterinary Research Communications. ,vol. 13, pp. 257- 263 ,(1989) , 10.1007/BF00420832
A. Horadagoda, P.D. Eckersall, J.C. Hodgson, H.A. Gibbs, G.M. Moon, Immediate responses in serum tnfα and acute phase protein concentrations to infection with Pasteurella haemolytica A1 in calves Research in Veterinary Science. ,vol. 57, pp. 129- 132 ,(1994) , 10.1016/0034-5288(94)90094-9
P. D. Eckersall, J. G. Conner, Bovine and canine acute phase proteins Veterinary Research Communications. ,vol. 12, pp. 169- 178 ,(1988) , 10.1007/BF00362798