Caspase inhibitors improve survival in sepsis: a critical role of the lymphocyte.
作者： R. S. Hotchkiss , K. C. Chang , P. E. Swanson , K. W. Tinsley , J. J. Hui
DOI: 10.1038/82741
关键词:
摘要: Sepsis induces lymphocyte apoptosis and prevention of lymphocyte death may improve the chances of surviving this disorder. We compared the efficacy of a selective caspase-3 …
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I H Chaudry, C C Baker, H O Gaines, A E Baue, Evaluation of factors affecting mortality rate after sepsis in a murine cecal ligation and puncture model. Surgery. ,vol. 94, pp. 331- 335 ,(1983)
Stephen R. Grobmyer, Robert C. Armstrong, Susan C. Nicholson, Cem Gabay, William P. Arend, Strite H. Potter, Maxine Melchior, Lawrence C. Fritz, Carl F. Nathan, Peptidomimetic fluoromethylketone rescues mice from lethal endotoxic shock. Molecular Medicine. ,vol. 5, pp. 585- 594 ,(1999) , 10.1007/BF03402071
Yee-Shin Lin, Huan-Yao Lei, Kuen-Jeng Huang, Shulhn-Der Wang, Sepsis-induced apoptosis of the thymocytes in mice. Journal of Immunology. ,vol. 152, pp. 5014- 5021 ,(1994)
J Goronzy, J Quan, C Weyand, P O'Hanley, C G Fathman, Enhanced cell-mediated protection against fatal Escherichia coli septicemia induced by treatment with recombinant IL-2. Journal of Immunology. ,vol. 142, pp. 1134- 1138 ,(1989)
Stanley A. Plotkin, Joseph M. Campos, Louis M. Bell, Gershon Alpert, Routine quantitative blood cultures in children with Haemophilus influenzae or Streptococcus pneumoniae bacteremia. Pediatrics. ,vol. 76, pp. 901- 904 ,(1985)
Timothy G. Buchman, Irene E. Karl, J. Perren Cobb, Dale F. Osborne, Katherine C. Chang, Paul E. Swanson, Richard S. Hotchkiss, C. Michael Knudson, Stanley J. Korsmeyer, Kimberly M. Zollner, Overexpression of Bcl-2 in Transgenic Mice Decreases Apoptosis and Improves Survival in Sepsis Journal of Immunology. ,vol. 162, pp. 4148- 4156 ,(1999)
J.S. Braun, R. Novak, K.-H. Herzog, S.M. Bodner, J.L. Cleveland, E.I. Tuomanen, Neuroprotection by a caspase inhibitor in acute bacterial meningitis. Nature Medicine. ,vol. 5, pp. 298- 302 ,(1999) , 10.1038/6514
Shiv Pillai, Abul K. Abbas, Andrew H. Lichtman, Cellular and Molecular Immunology ,(1994)
R. S. Hotchkiss, R. S. Rust, C. S. Dence, T. H. Wasserman, S. K. Song, D. R. Hwang, I. E. Karl, M. J. Welch, Evaluation of the role of cellular hypoxia in sepsis by the hypoxic marker [18F]fluoromisonidazole. American Journal of Physiology-regulatory Integrative and Comparative Physiology. ,vol. 261, ,(1991) , 10.1152/AJPREGU.1991.261.4.R965
P Yagupsky, F S Nolte, Quantitative aspects of septicemia. Clinical Microbiology Reviews. ,vol. 3, pp. 269- 279 ,(1990) , 10.1128/CMR.3.3.269