Study on the prevalence of phenylketonuria in Jordan and assessment of follow-up efforts and dietary management of patients with this disease

摘要: The objective of this research was to collect data on the prevalence phenylketonuria in Jordan, assess nutritional status and physical growth a sample PKU patients Jordan using anthropometric measurements evaluation adequacy their diets. Twenty five were divided, according age, into four groups: 4-6 months age (n = 6), 8-12 5), 2 years old 7) 4 7). Height, weight, triceps subscapular skinfold thicknesses measured. Dietary intake taken three-day food records, blood phenylalanine (Phe) concentration determined. results indicated that 48% whole had poor growth; about (66%) group 1, (40%) 2, (28%) 3 (57%) underweight. Significant positive correlations (p < 0.05) found between protein each head circumference (r 0.434) weight (0.420) height 0.502) patients. intakes 77% 88% recommended levels for groups 1 respectively. Other low dietary included energy (in 4), fat 3) selenium 1). All controlled Phe except those (4 age) who 358mol/L. It is concluded there need counseling community relationship consanguineous marriages stressing importance monitoring management